Advanced Services

Embryology Procedures

Cocoon Fertility is equipped with state-of-the-art facilities to offer the most recent embryology surgeries, which include the following:

In vitro Maturation of Eggs (IVM)


In IVF treatment, injections are given to obtain eggs from ovaries. Some of the eggs collected may be immature and these eggs are matured in the laboratory before being fertilized. Thus the total number of eggs that can be fertilized is increased. IVM is suitable for patients suffering from PolyCystic Ovarian Syndrome (PCOS) and those at risk of Ovarian Hyper - Stimulation Syndrome (OHSS).

LASER Assisted Hatching

Before an embryo can attach to the walls of the womb, it has to break out or hatch from its outer layer called the zona pellucida. Assisted hatching is performed while the embryo is in the laboratory. Before being transferred back to the womb a hole is made in the outer layer of the embryo or it is thinned, using a laser. This helps the embryo hatch and increases the chances of successful implantation which increases pregnancy rates. In safe and experienced hands, this procedure keeps the embryo safe as the outer layer is operated on.


LASER -assisted ICSI differs from conventional ICSI. In this procedure, lasers are used to drill a small hole through the hard outer coating of the egg and a single sperm is then injected into the egg. The hole eliminates the compression of the egg that normally occurs with conventional ICSI. This in turn lowers the risk of damage, increases egg survival and ensures better embryo quality.

Blastocyst Culture & Transfer

Most embryo transfers are performed on Day 3 of IVF. When an embryo is cultured in the lab for 5 to 6 days it forms a blastocyst. Blastocyst culture allows for the better selection of the embryos to be transferred and only requires a smaller number of embryos transfers to achieve a pregnancy. This helps to lower the risk of a multiple pregnancy.


Intracytoplasmic Morphological Sperm Injection (IMSI) is a technique in which sperm samples are examined under a microscope that is almost 6000 times more powerful than normal ICSI microscopes. This technique enables the fertility experts to choose the best quality sperm, without any defects, to inject into the egg, thereby improving the prospects of implantation and pregnancy. IMSI is indicated when the sperm sample is severely abnormal, when at least 2 previous ICSI treatments have failed or there is recurrent first trimester pregnancy loss after ICSI.


Only mature sperm have the capacity to bind to a mature egg. This binding capacity can be ascertained by the PICSI technique, allowing for only normal mature sperm with intact DNA, to be selected to perform ICSI with, thus increasing the chances of getting a better quality embryo and thus better chances at pregnancy.

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