Everything You Need To Know About Preimplantation Genetic Diagnosis (PGD)

Sep 14, 2017

What is PGD?

Preimplantation genetic testing is a technique used to identify genetic defects in embryos created through in vitro fertilization (IVF) before pregnancy. Preimplantation genetic diagnosis (PGD) refers specifically to when one or both genetic parents has a known genetic abnormality and testing is performed on an embryo to determine if it also carries a genetic abnormality.

How is the PGD performed?

PGD begins with the normal process of IVF that includes egg retrieval and fertilization with sperm in a laboratory. Over the next three days the embryo will divide into eight cells. First, one or two cells are removed from the embryo. The cells are then evaluated to determine if the inheritance of a problematic gene is present in the embryo. Once the PGD procedure has been performed and embryos free of genetic problems have been identified, the embryo will be placed back in the uterus, and implantation will be attempted. Any additional embryos that are free of genetic problems may be frozen for later use while embryos with the problematic gene are destroyed.

Who can benefit from PGD?

PGD can benefit any couple at risk for passing on a genetic disease or condition.

Individuals who can possibly benefit from PGD include -

• Carriers of sex-linked genetic disorders

• Carriers of single gene disorders

• Those with known chromosomal disorders

• Women age 35 and over

• Women experiencing recurring pregnancy loss

• Women with recurrent failed fertility treatment

This service will soon be introduced at Cocoon Fertility for the benefit of our clients.

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